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. 2017 Nov 30;12(11):e0188497. doi: 10.1371/journal.pone.0188497

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© 2017 Stalvey et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Cftr-/- rats are notably smaller in size compared to their wild type (WT) littermates. Animal total body weights are demonstrated versus age of the animals in Cftr-/- rats (•) compared to WT rats (▯). These findings are consistent with previously published data by Tuggle et al [13]. (B) Excised femurs obtained at sacrifice were measured by digital calipers. Femur length is reduced in Cftr-/- rats (•) compared to WT rats (▯) regardless of age or gender (p<0.0001).