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. 2017 Nov 30;12(11):e0188497. doi: 10.1371/journal.pone.0188497

Table 1. Micro CT of femurs.

Measurement (n) Female WT (7) Female Cftr-/- (6) Male WT (7)(7) Male Cftr-/- (10)
Trabecular total volume (mm3) 19.37±0.8 13.81±0.5**** 19.37±1.4 15.76±0.9*
Trabecular bone volume (mm3) 2.49±0.2 0.81±0.1*** 1.46±0.3 0.66±0.1**
Trabecular bone volume/total volume 0.13±0.01 0.06±0.01*** 0.073±0.01 0.042±0.01*
Trabecular number (1/mm) 2.85±0.2 1.54±0.1*** 1.72±0.2 1.45±0.1
Trabecular thickness (mm) 0.057±0.001 0.051±0.002* 0.051±0.002 0.049±0.001
Trabecular spacing (mm) 0.38±0.04 0.70±0.07** 0.63±0.05 0.76±0.06
Trabecular bone density (mgHA/cm3) 899.5±7 881.5±19 866.8±12 855.0±20
Cortical total volume (mm3) 4.89±0.1 3.58±0.2**** 4.80±0.3 3.82±0.3*
Cortical bone volume (mm3) 2.26±0.1 1.49±0.2** 1.92±0.3 1.31±0.2
Cortical bone volume/total volume 0.46±0.02 0.41±0.03 0.39±0.03 0.33±0.03
Cortical thickness (mm) 0.81±0.02 1.14±0.08** 0.81±0.05 1.07±0.08*
Cortical bone density (mgHA/cm3) 1231±1 1228±2 1186±2 1185±2
Connective density (1/mm3) 79.11±4.2 34.00±7.2*** 38.83±5.7 22.83±4.7*

(*p <0.05, **p <0.01, ***p <0.001, ****p <0.0001)