Table 1. Micro CT of femurs.
Measurement (n) | Female WT (7) | Female Cftr-/- (6) | Male WT (7)(7) | Male Cftr-/- (10) |
---|---|---|---|---|
Trabecular total volume (mm3) | 19.37±0.8 | 13.81±0.5**** | 19.37±1.4 | 15.76±0.9* |
Trabecular bone volume (mm3) | 2.49±0.2 | 0.81±0.1*** | 1.46±0.3 | 0.66±0.1** |
Trabecular bone volume/total volume | 0.13±0.01 | 0.06±0.01*** | 0.073±0.01 | 0.042±0.01* |
Trabecular number (1/mm) | 2.85±0.2 | 1.54±0.1*** | 1.72±0.2 | 1.45±0.1 |
Trabecular thickness (mm) | 0.057±0.001 | 0.051±0.002* | 0.051±0.002 | 0.049±0.001 |
Trabecular spacing (mm) | 0.38±0.04 | 0.70±0.07** | 0.63±0.05 | 0.76±0.06 |
Trabecular bone density (mgHA/cm3) | 899.5±7 | 881.5±19 | 866.8±12 | 855.0±20 |
Cortical total volume (mm3) | 4.89±0.1 | 3.58±0.2**** | 4.80±0.3 | 3.82±0.3* |
Cortical bone volume (mm3) | 2.26±0.1 | 1.49±0.2** | 1.92±0.3 | 1.31±0.2 |
Cortical bone volume/total volume | 0.46±0.02 | 0.41±0.03 | 0.39±0.03 | 0.33±0.03 |
Cortical thickness (mm) | 0.81±0.02 | 1.14±0.08** | 0.81±0.05 | 1.07±0.08* |
Cortical bone density (mgHA/cm3) | 1231±1 | 1228±2 | 1186±2 | 1185±2 |
Connective density (1/mm3) | 79.11±4.2 | 34.00±7.2*** | 38.83±5.7 | 22.83±4.7* |
(*p <0.05, **p <0.01, ***p <0.001, ****p <0.0001)