Fig 12. The effect of CK-666, an inhibitor of Arp2/3, on actin-pl-clusters, showing that the number of actin-pl-clusters quickly decreased, within 20 s, to the levels of ~20% and ~7.2% of those found before the CK-666 addition.

(A) Representative snapshots from image sequences of NRK cells transfected with Lifeact-mGFP and observed by TIRFM before (Left) and 20 s after the addition of CK-666 (Right). Control, treated only with DMSO. (B) The number of actin-pl-clusters observed per cell at 20 s after the CK-666 treatment vs. that before the treatment. The error bars indicate the standard errors (n = 6 cells for each condition).