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. 2017 Nov 30;12(11):e0188871. doi: 10.1371/journal.pone.0188871

Fig 2. Exposure to mono-oxidase inhibitors reduces ERRα half-life.

Fig 2

a. Expression of ERRα protein in MDA-MB231 cells after treatment with pargyline for the indicated time. b. Expression of ERRα protein in HeLa cells upon treatment with tranylcypromine for the indicated time. c. Steady state level of ERRα protein in HeLa cells was analyzed upon cycloheximide (CHX) treatment (50 μg/ml) for the indicated time, in the presence of Pargyline (Parg) or vehicle. d. Analysis of ERRα protein levels in HeLa cells after treatment with CHX, pargyline and MG132. Western blots were performed with the indicated antibodies. Quantification of ERRα levels (relative to hsp90) is displayed. Experiments were performed three times.