Table 1. Patients’ characteristics and prognostic factors of the survivors and non-survivors, and according to AKIN stage.
| Total (n = 216) |
Survivors (n = 40) |
Non-survivors (n = 176) |
p-value | AKIN0 (n = 26) |
AKIN1 (n = 15) |
AKIN2 (n = 26) |
AKIN3 (n = 149) |
p-value | |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 52.8±15.0 | 54.3±14.2 | 52.5±15.2 | 0.550 | 53.0±17.3 | 59.3±14.8 | 55.8±17.8 | 51.6±14.0 | 0.221 |
| Sex (male:female) | 186:30 | 36:4 | 150:26 | 0.593 | 24:2 | 11:4 | 20:6 | 131:18 | 0.163 |
| TBSA burned (%) | 55.8±25.2 | 35.3±23.4 | 60.4±23.3 | <0.001 | 66.3±24.3 | 60.5±25.9 | 45.3±25.4 | 55.3±24.7 | 0.016 |
| Inhalation Injury | 103(47.7%) | 16(40.0%) | 87(49.4%) | 0.367 | 13(50.0%) | 8(53.3%) | 9(34.6%) | 73(49.0%) | 0.546 |
| Weight | 68.2±11.3 | 68.7±8.9 | 68.1±11.7 | 0.438 | 67.2±13.8 | 67.5±9.5 | 65.0±10.7 | 69.0±11.0 | 0.320 |
| ABSI score | 10.6±2.5 | 8.5±2.5 | 11.1±2.3 | <0.001 | 11.8±2.2 | 11.3±2.7 | 9.7±2.5 | 10.5±2.5 | 0.009 |
| APACHE of admission | 52.4±18.9 | 47.2±18.6 | 53.6±18.8 | 0.117 | 53.6±13.2 | 45.9±18.9 | 58.6±15.2 | 51.8±20.1 | 0.074 |
| SAPS of admission | 42.7±9.9 | 38.6±9.8 | 43.6±9.7 | 0.003 | 42.6±8.4 | 40.7±12.3 | 45.1±10.1 | 42.5±9.9 | 0.975 |
| LOSICU (days) | 28.9±28.5 | 58.9±32.7 | 22.1±22.6 | <0.001 | 30.2±37.5 | 22.7±12.0 | 24.4±20.8 | 30.1±29.2 | 0.896 |
| LOS (days) | 34.3±37.5 | 87.6±43.4 | 22.2±22.6 | <0.001 | 36.7±44.8 | 22.7±12.0 | 25.9±21.8 | 36.5±39.8 | 0.898 |
| CRRT | |||||||||
| Initiation day | 12.4±13.3 | 16.2±12.2 | 11.6±13.4 | 0.011 | 10.6±6.5 | 13.0±9.4 | 15.1±16.0 | 12.2±14.0 | 0.767 |
| Intensity(mL/kg/h) | 30.1±4.7 | 29.6±4.0 | 30.2±4.8 | 0.438 | 31.0±6.5 | 30.2±4.1 | 31.5±5.0 | 29.6±4.3 | 0.320 |
| Duration (days) | 11.7±13.6 | 20.8±16.7 | 9.6±11.9 | <0.001 | 8.0±9.0 | 9.9±10.2 | 8.5±9.7 | 13.1±14.9 | 0.148 |
| Sepsis | 121(56.0%) | 22(55.0%) | 99(56.2%) | 1.000 | 13(50.0%) | 9(60.0%) | 11(42.3%) | 88(59.1%) | 0.388 |
| APACHE III at start | 70.7±18.6 | 60.0±15.6 | 73.2±18.4 | <0.001 | 56.5±16.0 | 69.9±18.8 | 66.6±19.3 | 74.0±17.7 | <0.001 |
| SAPS II at start | 49.4±10.8 | 42.7±9.1 | 50.9±10.6 | <0.001 | 45.8±9.8 | 49.0±8.5 | 48.2±13.2 | 50.2±10.7 | 0.055 |
| SOFA at start | 8.8±2.9 | 7.0±2.4 | 9.2±2.9 | <0.001 | 7.1±3.1 | 7.9±3.0 | 8.5±3.0 | 9.2±2.7 | 0.003 |
| MAP | 59.5±17.0 | 74.4±19.9 | 56.0±14.2 | <0.001 | 64.8±18.2 | 56.9±15.5 | 60.7±14.5 | 58.6±17.3 | 0.403 |
| Supportive cares | |||||||||
| Ventilator | 197(91.2%) | 26(65.0%) | 171(97.2%) | <0.001 | 24(92.3%) | 15(100%) | 25(96.2%) | 133(89.3%) | 0.395 |
| Vasopressors | 133(61.6%) | 14(35.0%) | 119(67.6%) | <0.001 | 14(53.8%) | 10(66.7%) | 17(65.4%) | 92(61.7%) | 0.806 |
| Prognostic Factors | |||||||||
| pH | 7.23±0.09 | 7.26±0.09 | 7.20±0.08 | <0.001 | 7.24±0.08 | 7.22±0.07 | 7.23±0.11 | 7.20±0.08 | 0.038 |
| Potassium (mEq/L) | 4.7±0.8 | 4.5±0.7 | 4.8±0.8 | 0.104 | 4.6±0.7 | 4.6±0.6 | 4.6±0.9 | 4.8±0.8 | 0.386 |
| BUN (mg/dL) | 42.7±17.7 | 41.6±15.2 | 42.9±18.2 | 0.890 | 42.4±18.0 | 38.6±22.6 | 38.1±16.5 | 43.9±17.2 | 0.264 |
| Creatinine (mg/dL) | 2.2±1.4 | 2.9±2.1 | 2.0±1.1 | 0.002 | 1.1±0.4 | 1.2±0.5 | 1.6±0.7 | 2.6±1.5 | <0.001 |
| Urine/kg/h (cc) | 0.7±0.6 | 0.8±0.7 | 0.7±0.5 | 0.300 | 1.5±0.7 | 1.1±0.4 | 0.7±0.4 | 0.5±0.4 | <0.001 |
| Lactate (mmol/L) | 2.5±1.8 | 1.7±1.2 | 2.7±1.9 | <0.001 | 2.1±1.3 | 2.7±1.7 | 3.1±2.7 | 2.5±1.7 | 0.378 |
| WBC (x103/μL) | 17.1±10.2 | 16.5±11.9 | 17.2±9.8 | 0.377 | 14.8±9.1 | 18.5±9.9 | 15.6±9.6 | 17.6±10.5 | 0.296 |
| Platelet (x103/μL) | 109.0±96.6 | 168.2±127.8 | 95.5±82.7 | <0.001 | 131.5±136.6 | 136.9±117.1 | 103.9±76.3 | 103.1±89.0 | 0.582 |
| PF ratio | 159.4±87.2 | 197.8±63.1 | 150.7±89.6 | <0.001 | 146.4±75.5 | 146.0±98.3 | 161.9±97.9 | 162.6±86.5 | 0.725 |
| TB (mg/dL) | 1.5±1.4 | 1.1±0.9 | 1.6±1.5 | 0.026 | 1.1±1.4 | 1.8±1.4 | 1.9±1.9 | 1.5±1.3 | 0.014 |
| Mortality | 176(81.5%) | 20(76.9%) | 15(100%) | 23(88.5%) | 118(79.5%)2 | 0.163 |
n, number; FB, Flame Burn; SB, Scald Burn; EB, Electrical Burn; ChB, Chemical Burn; CoB, Contact Burn; %TBSA burned, percentage of total body surface area burned; LOSICU, length of stay in ICU stay; LOS, length of hospital stay