Figure 4.

Correlation of somatosensory and motor anatomy and physiology with hand function. Movement tests (Jebsen Taylor, Box & Blocks and AHA) are shown in the left panel and sensation tests (Stereognosis and 2-point Discrimination) in the right. (A) Somatosensory Connectivity: The presence or absence of physiological connectivity in injured cortex, as measured with SEPs, was significantly correlated with all movement and sensation tests. The absence of a SEP was associated with poor hand function. The presence or absence of anatomical connections in injured cortex, as seen with DTI was significantly correlated with hand function for all test except AHA. Absence of tracts was associated with poor hand function.

(B) Motor Connectivity: The presence of predominant contralateral or ipsilateral physiological connections, as measured by TMS, was not significantly correlated with most movement and sensation test scores, except AHA. The presence or absence of anatomical connections in injured cortex, as seen in DTI, were not significantly correlated with hand function tests, except Stereognosis. The absence of the crossed CST was associated only with poor stereognosis. Significance was estimated by a non-parametric permutation test: *** = p < 0.001, ** = p < 0.01, * = p < 0.05. (Colored version of Figure is available online)