Table 1.

Effects of developmental treatment with corticosterone (CORT) from days 12–28 post-hatch on circulating CORT and immune parameters.

	Dependent Variable	CORT Treatment				Hatch Date				Hatch Order				Clutch #
Day		N	Est	SE	P	N	Est	SE	P	N	Est	SE	P	N	Est	SE	P
14	Baseline CORT	100	0.63	0.05	<0.001
	BKA	31	0.02	0.07	0.810	31	0.00	0.0	0.030	31	0.08	0.03	0.020
36	BKA	116	0.03	0.04	0.500					116	0.03	0.04	0.055
60	Baseline CORT	98	0.07	0.09	0.420
	Stress CORT	99	0.0	0.09	0.970									99	0.1	0.05	0.047
	BKA	25	0.01	0.05	0.850	25	0.00	0.0	0.001
68	Anti-LPS Ab	57	0.02	0.28	0.940
100	Baseline Hp	85	0.02	0.01	0.100									85	0.02	0.01	<0.001
	12-Hr Hp	83	0.0	0.01	0.940	83	0.00	0.00	0.001
108	Anti-LPS Ab	43	0.08	0.55	0.880	43	0.01	0.00	0.005

CORT dosing elevated circulating CORT concentrations during the treatment period (i.e., day 14) but did not impact subsequent CORT concentrations, either baseline or concentrations produced in response to lipopolysaccharide (LPS) challenge (LPS CORT). Developmental CORT treatment also did not significantly affect immune parameters. BKA=Bacteria killing ability, Anti-LPS Ab=specific antibodies to LPS, Hp=haptoglobin, 12-Hr Hp=haptoglobin concentrations measured 12 hours after LPS challenge. Est is the model estimate (slope of the relationship) between parameters. Significant (p<0.05) effects are bolded.