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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Cancer Metastasis Rev. 2017 Sep;36(3):411–423. doi: 10.1007/s10555-017-9689-6

Table 3.

Compounds in tobacco smoke that have been evaluated as carcinogens in either laboratory animals or humans by the International Agency for Research on Cancer. BaP, benzo[a]pyrene; NNK, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; NNN, N′-nitrosonornicotine. Khariwala et al. 2012 [31].

Chemical class No. of compounds Representative carcinogens
Polycyclic aromatic hydrocarbons 19 graphic file with name nihms899518t1.jpg graphic file with name nihms899518t2.jpg
Nitrosamines 8 graphic file with name nihms899518t3.jpg graphic file with name nihms899518t4.jpg
Aromatic amines 13 graphic file with name nihms899518t5.jpg graphic file with name nihms899518t6.jpg
Aldehydes 2 CH2 = 0
formaldehyde		 CH3CHO
acetaldehyde
Various hydrocarbons 6 graphic file with name nihms899518t7.jpg graphic file with name nihms899518t8.jpg
Other organics 15 graphic file with name nihms899518t9.jpg graphic file with name nihms899518t10.jpg
Inorganic compounds 9 cd 2HPo
Total 72
HHS Vulnerability Disclosure