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Correction of thrombin generation by S195A GD-FXa in FVIII-immuno-depleted plasma. FVIII-immuno-depleted plasma (Stago) was spiked with S195A GD-FXa at low tissue factor concentration: 1 pM tissue factor and 4 μM phospholipids [PPP-reagent low, (Stago), final concentration]. The positive control was made with recombinant FVIII (Octocog alpha, Bayer).
