Table 4.

Intra-day and inter-day accuracy and precision of four bioactive ingredients in rat urine and feces QC samples

Matrix	Analytes	Concentration (μg mL−1)		Precision (RSD, %)		Accuracy (RE, %)
		Spiked	Measured (mean ± SD)	Intra-day	Inter-day	Intra-day	Inter-day
Urine	GPS	8.32	8.44 ± 0.13	1.5	6.3	1.4	− 2.5
		5.10	5.19 ± 0.24	4.7	4.6	1.8	− 1.2
		1.87	2.21 ± 0.50	14.9	14.4	− 8.1	6.6
	LOG	9.71	10.9 ± 0.07	0.7	2.9	3.9	0.7
		6.07	6.84 ± 0.17	2.4	7.4	12.8	− 3.3
		2.43	1.77 ± 0.13	4.6	16.2	7.7	4.2
	SWM	5.60	4.77 ± 0.25	5.2	6.7	− 14.9	− 6.5
		3.98	3.11 ± 0.16	5.0	3.1	− 15.1	− 6.9
		2.35	2.54 ± 0.39	15.5	9.5	7.9	− 7.8
	SWS	4.00	3.86 ± 0.84	3.9	1.3	− 12.4	5.5
		3.10	3.28 ± 0.04	1.1	10.0	5.8	2.5
		2.20	2.49 ± 0.15	5.8	17.6	13.3	− 7.3
Feces	GPS	7.99	8.04 ± 0.39	5.2	4.9	1.3	0.6
		4.89	4.80 ± 0.12	2.4	2.5	− 0.4	− 2.0
		1.80	1.70 ± 0.04	4.8	2.6	1.2	− 5.4
	LOG	9.32	9.38 ± 0.08	0.8	6.8	0.6	2.9
		5.82	5.77 ± 0.02	0.3	3.6	− 0.9	2.4
		2.33	2.26 ± 0.01	0.7	6.1	− 3.2	8.3
	SWM	5.38	5.02 ± 0.36	7.3	3.0	− 6.6	− 0.6
		3.82	3.38 ± 0.07	2.1	4.9	− 11.4	− 1.8
		2.26	2.00 ± 0.09	4.7	7.7	− 11.2	− 0.6
	SWS	3.84	4.06 ± 0.21	2.0	3.6	5.8	− 0.3
		2.98	2.50 ± 0.09	12.3	13.6	− 4.5	− 2.3
		2.11	1.92 ± 0.03	1.4	9.1	− 9.1	− 3.5