Table 5.
mRNA levels of genes related to mitochondrial biogenesis and inflammation in the myometrium at term of the normal weight group (18.5 < BMI < 25 kg m−2) and obese group (BMI ≥ 30 kg m−2)
| Normal wt | Obese | ||
|---|---|---|---|
| (n = 19) | (n = 17) | P | |
| CD68 (mRNA, AU) | 1.23 ± 0.12 | 1.02 ± 0.34 | 0.127 |
| PGC‐1α (mRNA, AU) | 1.14 ± 0.26 | 1.80 ± 0.16 | 0.120 |
| PGC‐1β (mRNA, AU) | 1.07 ± 0.09 | 1.10 ± 0.09 | 0.827 |
| PPAR‐γ (mRNA, AU) | 1.30 ± 0.19 | 1.27 ± 0.12 | 0.839 |
| TFAM (mRNA, AU) | 1.31 ± 0.07 | 1.30 ± 0.75 | 0.513 |
| CPT1A (mRNA, AU) | 1.09 ± 0.07 | 1.17 ± 0.71 | 0.997 |
RNA levels of genes related to mitochondrial biogenesis and inflammation measured by quantitative real‐time PCR in the myometrium at term normalized to GAPDH mRNA levels grouped by BMI. CD68, cluster of differentiation 68; PGC‐1α, peroxisome proliferator‐activated receptor γ coactivator 1 α; PCG‐1β, peroxisome proliferator‐activated receptor γ coactivator 1 β; PPAR‐γ, peroxisome proliferator‐activated receptor γ; TFAM, mitochondrial transcriptional factor A; CPT1A carnitine palmitoyltransferase 1A. Results are given as mean ± SEM. Data were log‐transformed prior to analysis and significance of difference between groups was evaluated by Student's t test; no significant difference between groups was found.