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. 2017 Nov 30;7:16650. doi: 10.1038/s41598-017-16932-y

Figure 7.

Figure 7

Successful differentiation of wildtype naïve hESCs to neural progenitor cells (NPCs). (a) Pluripotency markers (OCT3/4, REX1, SOX2 and NANOG) decrease during neural differentiation of wildtype naïve hESCs, while the expression of neural progenitor cell markers (PAX6, NESTIN, NEURDO1, SOX1) increases (b). Expression of TUNA increases during first two days (c). RNA was sampled at day 0, 2, 4, 6 and 8 of neural induction. Average CNRQ ± standard error of three independent biological replicates is shown.