Table 4.
Symptoms reported spontaneously, selected as most bothersome, and indicative of a diabetic gastroparesis (DGP) medication working (n = 73)
| Symptom | Spontaneous reportsa | Selected as most bothersomeb,c | Indicative of DGP medication workingd,e |
|---|---|---|---|
| Bloating | 51 (69.9%) | 20 (27.4%) | 36 (49.3%) |
| Stomach fullness | 43 (58.9%) | 5 (6.8%) | 14 (19.2%) |
| Constipation | 39 (53.4%) | 8 (11.0%) | 15 (20.5%) |
| Vomiting | 39 (53.4%) | 5 (6.8%) | 10 (13.7%) |
| Upper abdominal pain | 38 (52.1%) | 12 (16.4%) | 13 (17.8%) |
| Heartburn or reflux | 38 (52.1%) | 5 (6.8%) | 7 (9.6%) |
| Nausea | 36 (49.3%) | 11 (15.1%) | 16 (21.9%) |
| Gas | 35 (47.9%) | 4 (5.5%) | 6 (8.2%) |
| Diarrhea | 28 (38.4%) | 2 (2.7%) | 6 (8.2%) |
| Regurgitation | 22 (30.1%) | 1 (1.4%) | 1 (1.4%) |
| Cramping | 18 (24.7%) | 3 (4.1%) | 4 (5.5%) |
| General abdominal pain/discomfort | 18 (24.7%) | 1 (1.4%) | – |
| Upper abdominal discomfort | 16 (21.9%) | 2 (2.7%) | 4 (5.5%) |
| Postprandial fullness | 15 (20.5%) | 1 (1.4%) | – |
| Retching | 7 (9.6%) | 1 (1.4%) | – |
aSpontaneous reports provided only for symptoms selected among the most bothersome
bThe sum of reports is more than 73 as some participants reported more than one most bothersome symptom
cTwo participants were unable to respond, noting that all of their DGP symptoms were the most bothersome
dThe sum of reports is more than 73 as some participants reported more than one symptom needing to improve
eAdditional symptoms that participants reported would indicate that a DGP medication was working included stomach or belly visibly larger (n = 3; 4.1%), lower abdominal pain (n = 1; 1.4%), and regurgitation (n = 1; 1.4%)