Fig. 4. Changes in (A) p-PERK, and (B) GRP78 (blue) and CHOP (red) protein expression levels in the cardiac muscle after 8 weeks of diet and/or exercise intervention.

(A) ⁺Significantly different from CD (p < 0.05); ^*Significantly different from CD, CE, FE (p<0.05). (B) ⁺Significantly different from CD, FE (p<0.05); ^*Significantly different from CD, CE, FE (p<0.05). CD, normal chow diet; CE, chow diet+exercise; FD, high-fat diet only; FE, high-fat diet+exercise.