Table 2. Independent risk factors for PAN metastasis.
| Variables | aOR (95% CI) | p-value | |
|---|---|---|---|
| Tumor size (cm) | |||
| ≤4.0 | 1.00 | - | |
| >4.0 | 0.96 (0.33–2.78) | 0.930 | |
| Parametrial involvement | |||
| No | 1.00 | - | |
| Yes | 1.65 (1.01–2.70) | 0.046 | |
| Deep stromal invasion | |||
| No | 1.00 | - | |
| Yes | 2.61 (1.05–6.46) | 0.038 | |
| LVSI | |||
| Absence | 1.00 | - | |
| Presence | 0.97 (0.47–2.03) | 0.940 | |
| Corpus invasion | |||
| No | 1.00 | - | |
| Yes | 0.95 (0.57–1.60) | 0.850 | |
| Ovarian metastasis | |||
| No | 1.00 | - | |
| Yes | 3.10 (1.33–7.23) | 0.009 | |
| Cytology results | |||
| No malignancy | 1.00 | - | |
| Malignancy | 1.61 (0.71–3.68) | 0.260 | |
| Not performed | 0.72 (0.44–1.17) | 0.180 | |
| PLN | |||
| No metastasis | 1.00 | - | |
| Single metastasis | 5.39 (1.74–16.6) | 0.003 | |
| Multiple metastasis | 33.5 (13.7–81.8) | <0.001 | |
A multivariate logistic regression model for PAN metastasis. Significant covariates on univariate analysis were entered in the final model. Significant p-values were emboldened. Clinical stage was not entered due to multicollinearity. Hosmer-Lemeshow test p=0.74, indicating goodness-of-fit in the final model.
aOR, adjusted odds ratio; CI, confidence interval; LVSI, lympho-vascular space invasion; PAN, para-aortic lymph node; PLN, pelvic lymph node.