Table 5:

Summary Efficacy Estimates Used in the Economic Model

Model Parameter	Relative Risk (95% CI)	Distribution	Source
Risk of recurrence, MDD: CBT only vs. no treatment	0.68 (0.53–0.76)	Normal (log-odds ratio)	Biesheuvel-Leliefeld et al, 201529
Risk of recurrence, MDD: CBT plus pharmacotherapy vs. pharmacotherapy only	0.94a (0.72–1.21)	Normal (log-odds ratio)	Amick et al, 201536
Risk of recurrence, MDD: Individual CBT vs. group CBT	0.78b (0.69–0.93)	Normal (log-odds ratio)	Churchill et al, 200122
Risk of recurrence, GAD: CBT only vs. no treatment	0.67c (0.65–0.68)	Normal (log-odds ratio)	Cuijpers et al, 201620
Risk of recurrence, MDD: Interpersonal therapy only vs. no treatment	0.41 (0.27–0.63)	Normal (log-odds ratio)	Biesheuvel-Leliefeld et al, 201529
Risk of recurrence, second-generation antidepressant, sertraline	0.80 (0.69–0.93)	Normal (log-odds ratio)	Cipriani et al, 2009106

Abbreviations: CBT, cognitive behavioural therapy; CI, confidence interval; GAD, generalized anxiety disorder; MDD, major depressive disorder.

^aRecalculated from the reported relative risk of 1.06 (95% CI: 0.82–1.38).

^bRelative risk estimated from the odds ratio after accounting for a mean baseline probability of major depressive episode in the placebo arm of 0.57.¹⁰⁷

^cRelative risk calculated from Hedge's g statistic, using established methods after adjusting for baseline rate of event.¹⁰⁷