Figure 7.

(A) Nuclear bodies of PQBP1. PQBP1-EGFP (left) and PQBP1-RFP (right) are expressed in cell lines. Reproduced from Okazawa et al., Brain Res Bullet 2001.⁴⁵⁾ (B) PONDR analysis of the PQBP-1 that predicts C-terminal domain is disordered. Reproduced from Takahashi et al., Biochem Biophys Acta 2009.⁶⁷⁾ (C) The result from CD analysis of PQBP1 is typical for intrinsically disordered protein. Reproduced from Rees et al., Biophys J 2012.⁶⁸⁾ (D) Net charge versus hydropathy analysis predict PQBP1 is disordered. Plots are generated from database of folded (gray squares) and unfolded (open circles) proteins. PQBP-1 indicated with a black circle. Reproduced from Rees et al., Biophys J 2012.⁶⁸⁾