Table 1. Effects of Vit E, Vit C and its combination on soluble Klotho protein in plasma (ng/ml) and urine (ng/mg Cr).

Soluble Klotho	Group 1	Group 2	Group 3	Group 4	Group 5
Plasma Klotho	5.033 ± 2.224	1.091 ± 0.156a)	5.698 ± 2.095	1.447 ± 0.225	3.163 ± 1.254
Urine Klotho/UCr	0.603 ± 0.088	0.373 ± 0.122	0.592 ± 0.073	0.909 ± 0.264	4.451 ± 1.918b)

Data are shown as mean ± SEM. a) P<0.05 compared with group 1; b) P<0.05 compared with group 2 using One-way ANOVA. UCr=urinary creatinine.