FIG 5.

An sncRNA encoded by VZV interferes with VZV replication. Shown is quantification of the effect of transfection of an antagonist to VZVsncRNA23 1 day after infection of ARPE19 cells on the growth of individual infectious foci. The columns represent the increase in numbers of pixels representing fluorescence in antagonist-treated versus control RNA-treated wells. Seventy antagonist-treated and 80 control RNA-treated foci were analyzed, and the difference between the groups was significant (P < 0.001). Error bars represent the standard error of the mean.