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Env-specific T-cell responses. ICS was used to evaluate Env-specific CD4+ (A) and CD8+ (B) T cells in PBMC and Env-specific CD4+ T cells in axillary lymph nodes (C). Tests were done at 1 week following the 3rd boost. *, P < 0.05 for pairwise comparison (exact Wilcoxon rank sum test). All differences are insignificant once adjusted for multiple comparison (Table 2).
