FIG 2.
HPV16 infection induces massive changes in the keratinocyte transcriptome. (A) mRNA numbers expressed versus the level of expression of each individual mRNA in undifferentiated (U) versus differentiated (D) NIKS (HPV-negative) cells. (B) mRNA numbers expressed versus the level of expression of each individual mRNA in undifferentiated (U) versus differentiated (D) NIKS16 (HPV-positive) cells. (C) Venn diagram showing the percentage identity between upregulated genes of NIKS and NIKS16 cells and those of NIKS and W12 cells. (D) Venn diagram showing the percentage identity between downregulated genes of NIKS and NIKS16 cells and those of NIKS and W12 cells. Identity was determined using the GFOLD tool to calculate the differential fold changes of the two comparisons.