TABLE 2.

RNA-Seq expression changes in mRNAs of statistical significance (P <0.025) verified by qRT-PCR

Gene	Padj	NIKS16/NIKS fold change by RNA-Seq	NIKS16/NIKS fold change by qPCR	W12/NIKS fold change qPCR	Gene product/function
DSG1	2.05 × 10−5	−19.95	−4.20	−3.52	Desmoglein 1: calcium-binding desmosome regulator
IL1B	1	−8.68	−5.65	−7.73	Interleukin 1β: inflammatory response regulator
SERPINB3	0.008	−8.40	−4.28	−4.410	Intracellular protease inhibitor, inhibits active inflammatory response
KRT10	0.021	−7.07	−10.26	−3.70	Keratin 10: epithelial cytofilament
KDR	0.025	10.21	10.10	4.30	VEGFR-2, tyrosine kinase receptor
VTCN1	1.4 × 10−9	46.12	8.94	10.56	V-set domain-containing T-cell activation inhibitor-1
AZGP1	2.05 × 10−5	12.64	7.49	8.31	Zinc alpha-2 glycoprotein: lipid metabolism
GAPDH		1	1	1	Glyceraldehyde-3-phosphate dehydrogenase (control)
Beta-actin		1	1	1	Actin (control)