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HIV-1 with mixed Comb-mut/CM-LK Env trimers is neutralized completely by combining PG9 and PGT145
| Virus | PG9 |
PGT145 |
PG9+PGT145 |
|||
|---|---|---|---|---|---|---|
| IC50 (μg/ml) | MPN (%) | IC50 (μg/ml) | MPN (%) | IC50 (μg/ml) | MPN (%) | |
| Comb-mut | 0.27 | 92 | 0.08 | 100 | 0.01 | 100 |
| CM-LK | 0.03 | 100 | 1.00 | 82 | 0.03 | 100 |
| Comb-mut/CM-LK | 0.09 | 98 | 0.06 | 97 | 0.07 | 100 |
