TABLE 1.

Univariate and multivariate models

Model	Pneumococcal infection		Invasive pneumococcal infection
	Coefficient (95% CI)	p-value	Coefficient (95% CI)	p-value
Univariate
SO2	1.411 (0.94–1.881)	<0.0001	0.243 (0.088–0.398)	0.002
CO	9.303 (0.956–17.651)	0.03
O3	−0.08 (−0.115– −0.044)	<0.0001
NOx	0.103 (0.078–0.127)	<0.0001	0.009 (0.0003–0.018)	0.04
NO	0.261 (0.198–0.323)	<0.0001	0.025 (0.002–0.048)	0.04
NO2	0.208 (0.152–0.265)	<0.0001
PM1	−0.146 (−0.247– −0.045)	0.005
PM2.5	−0.122 (−0.2– −0.044)	0.002
PM10	−0.121 (−0.201– −0.04)	0.004
Relative humidity	−0.119 (−0.189– −0.05)	0.001
Temperature	−0.456 (−0.546– −0.367)	<0.0001	−0.073 (−0.108– −0.038)	<0.0001
Solar radiation	−0.029 (−0.039– −0.019)	<0.0001	−0.004 (−0.008– −0.001)	0.008
Multivariate
SO2	0.732 (0.342–1.121)	0.0003	0.158 (−0.005–0.322)	0.058
Temperature	−0.196 (−0.326– −0.065)	0.003	−0.052 (−0.090– −0.014)	0.008
Relative humidity	−0.054 (−0.105– −0.002)	0.04
NO	0.139 (0.065–0.212)	0.0003

PM_x: particles with a 50% cut-off aerodynamic diameter of _x μm.