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. 2017 Sep 22;7(9):e612. doi: 10.1038/bcj.2017.94

Figure 1.

Figure 1

Patient-specific mutational load. (a) Distribution of individual patient missense, nonsense, and frameshift somatic mutation counts for the 664 patient cohort. Box represents 25–75% of patients. Bolded line marks the median mutation count. (b) Histogram of natural log-transformed somatic missense mutation count shows log transformation normalizes the distribution of missense mutation frequency in patients.