Table 2.
Laboratory and ultrasonic data before and after SBT
| Respiratory failure within 48 h | ||
|---|---|---|
| Variables | RF subgroup | ES subgroup |
| N (cases) | 29 | 31 |
| Before SBT | ||
| PH | 7.45 ± 0.06 | 7.46 ± 0.05 |
| PaCO2 (mmHg) | 46.4 ± 13 | 39.1 ± 5.1* |
| PaO2/FiO2 | 277 ± 83 | 281 ± 80 |
| Lactic acid (mmol/l) | 1.2 ± 0.6 | 1.1 ± 0.4 |
| NT-pro-BNP(pg/ml) | 6519 ± 9162 | 1578 ± 1843* |
| Pleural effusion | 22 (76) | 24 (77) |
| LVEF (%) | 57 ± 14 | 64 ± 9* |
| E (cm/s) | 92.9 ± 25.6 | 78.2 ± 18.4* |
| E/Ea (septal) | 18.2 ± 8.1 | 13 ± 3.8* |
| E/Ea (lateral) | 12.8 ± 5.1 | 8.4 ± 2.7† |
| E/Ea (average) | 14.7 ± 5.6 | 10.1 ± 2.8† |
| DE (right) (mm) | 11.2 ± 4.7 | 10.1 ± 4.7 |
| DE (left) (mm) | 11.6 ± 6.3 | 10.8 ± 5.5 |
| DE (average) (mm) | 11.4 ± 4.5 | 10.5 ± 3.4 |
| After SBT | ||
| PH | 7.43 ± 0.05 | 7.47 ± 0.05* |
| PaCO2 (mmHg) | 48 ± 11.7 | 38.7 ± 5.5† |
| PaO2/FiO2 | 291 ± 103 | 275 ± 79 |
| Lactic acid (mmol/l) | 1.1 ± 0.5 | 1.1 ± 0.5 |
| NT-pro-BNP(pg/ml) | 6518 [421-10,477] | 1471[176-1575]* |
| E (cm/s) | 99.7 ± 24.3 | 85.1 ± 18.2* |
| E/Ea (septal) | 18.6 ± 6.5 | 13.4 ± 4.4* |
| E/Ea (lateral) | 14.4 ± 7.3 | 9.0 ± 3.0* |
| E/Ea (average) | 15.8 ± 6.2 | 10.6 ± 3.2† |
| DE (right) (mm) | 13.7 ± 6 | 11 ± 4.4 |
| DE (left) (mm) | 13.8 ± 6.4 | 13 ± 5.4 |
| DE (average) (mm) | 13.7 ± 5.4 | 12 ± 3.4 |
Data are presented as median ± SD or median (IQR) or n (%). DE diaphragmatic excursion, E mitral Doppler early peak diastolic velocity, E/Ea the ratio of mitral Doppler inflow velocity to annular tissue Doppler wave velocity, ES extubation success, LVEF left ventricular ejection fraction, NT-pro-BNP N-terminal-pro-B-type natriuretic peptide, PaCO 2 arterial carbon dioxide tension, PaO 2 /FiO 2 the ratio of arterial oxygen tension to fraction of inspired oxygen, RF respiratory failure, SBT spontaneous breathing trial. * Significant at p < 0.05, and † significant at p < 0.001