Fig. 9.
The ceRNA model was proposed to summarize lncRNA-H19/miR-29a-3p/E2F1 pathway. LncRNA-H19 negatively regulated miR-29a-3p in ccRCC, through binding to miR-29a-3p directly. In addition, miR-29a-3p targeted E2F1 and negatively regulated E2F1 expression, indicating that lncRNA-H19 could influence the expression of E2F1 in ccRCC through miR-29a-3p