Table 3.
Contributing signals for the DOCK8 gene from each psychiatric disease cohort
| Disease cohort | Overlapping CNV region (hg18) | CNV type | Odds ratio | P value | Number of case CNVs (%) | Number of control CNVs (%) |
|---|---|---|---|---|---|---|
| Janssen SCZ and BD | Chr9:396118-474850 | Dup | Infinity | 0.00693 | 6 (0.21) | 0 (0) |
| CHOP SCZ | Chr9:372245-389052 | Dup | 10.71 | 0.008 | 7 (0.73) | 1 (0.07) |
| CHOP ASD | Chr9:407918-474786 | Dup | Infinity | 0.00384 | 7 (0.34) | 0 (0) |
| CHOP ADHD | Chr9: 293639-352917 | Dup | 3.32 | 0.0899 | 4 (0.32) | 4 (0.10) |
| Depression | Chr9: 283360-294957 | Dup | 4.96 | 0.00731 | 8 (1.24) | 4 (0.25) |
Number of case CNVs is the number of cases having a DOCK8 duplication and the frequency among all cases. Number of control CNVs is the number of controls having a DOCK8 duplication CNV and the frequency among all controls