Table 1.
Biochemistry profile of healthy female guinea pigs (n = 4) after SRB administration
| After administration |
||||||||||
| Baseline |
SRBLow |
SRBMedium |
SRBHigh |
|||||||
| Units | Mean ± 1 SD | Range | Mean± 1 SD | Range | Mean ± 1 SD | Range | Mean ± 1 SD | Range | Reference range5,21 | |
| Total protein | g/dL | 5.36 ± 0.46 | 4.8–6 | 5.55 ± 0.53 | 5–6 | 5.1 ± 1.41 | 3.6–6 | 5.1 ± 0.35 | 4.8–5.4 | 4.5–7.1 |
| Albumin | g/dL | 3.14 ± 0.30 | 2.5–3.6 | 3.13 ± 0.46 | 2.5–3.6 | 2.7 ± 0.65 | 1.8–3.3 | 2.7 ± 0.35 | 2.4–3 | 2.3–4.8 |
| Globulin | g/dL | 2.22 ± 0.31 | 1.8–2.8 | 2.43 ± 0.33 | 2–2.8 | 2.4 ± 0.42 | 1.8–2.7 | 2.4 ± 0.00 | 2.4 | 1.7–2.6 |
| Albumin: globulin | — | 1.44 ± 0.23 | 1–1.7 | 1.3 ± 0.29 | 1–1.6 | 1.13 ± 0.15 | 1–1.3 | 1.15 ± 0.17 | 1–1.3 | — |
| AST | IU/L | 52.83 ± 10.04a | 39–69 | 49.5 ± 11.7a | 40–64 | 100.5 ± 59.32b | 42–183 | 86.25 ± 25.38b | 54–108 | 38–643 |
| ALT | IU/L | 34.17 ± 5.22 | 33–36 | 38 ± 2.94 | 35–41 | 38.5 ± 7.94 | 35–43 | 40.5 ± 7.14 | 37–45 | 32–138 |
| ALP | IU/L | 91.25 ± 19.17 | 69–120 | 106.5 ± 15.61 | 84–120 | 79.5 ± 13.3 | 71–81 | 72.5 ± 6.24 | 71–90 | 68–399 |
| GGT | IU/L | 8.33 ± 5.26 | 7–12 | 11.5 ± 0.58 | 8–13 | 9 ± 2.45 | 6–12 | 12.25 ± 6.65 | 9–14 | 3–14 |
| Total bilirubin | mg/dL | 0.10 ± 0.00 | 0.1 | 0.1 ± 0.00 | 0.1 | 0.1 ± 0.00 | 0.1 | 0.1 ± 0.00 | 0.1 | 0.1–0.8 |
| BUN | mg/dL | 22.00 ± 5.19 | 16–30 | 18.75 ± 7.54 | 15–30 | 21.75 ± 3.77 | 18–27 | 20.25 ± 1.5 | 18–21 | 15.7–31.5 |
| Creatinine | mg/dL | 0.48 ± 0.12 | 0.4–0.5 | 0.45 ± 0.13 | 0.4–0.5 | 0.55 ± 0.1 | 0.5–0.7 | 0.5 ± 0.00 | 0.5 | 0.4–1.8 |
| BUN:creatinine | — | 65.50 ± 28.27 | 30–120 | 60 ± 31.62 | 30–100 | 40.5 ± 10.25 | 30–54 | 40.5 ± 3 | 36–42 | — |
| Phosphorus | mg/dL | 6.04 ± 1.78 | 4.9–9.3 | 7.2 ± 1.21 | 5.4–8 | 5.63 ± 0.93 | 4.8–6.9 | 5.33 ± 1.28 | 4.9–6.9 | 4.2–15 |
| Glucose | mg/dL | 152.25 ± 59.19 | 129–192 | 95.75 ± 34.3 | 88–126 | 96.50±23.41 | 81–126 | 110.25 ± 9.91 | 96–117 | 80–546 |
| Calcium | mg/dL | 10.55 ± 0.60 | 9–11.4 | 10.38 ± 0.94 | 9–11.1 | 10.5 ± 0.88 | 9.3–11.4 | 10.43 ± 0.86 | 9.3–11.4 | 9.0–14.6 |
| Magnesium | mEq/L | 2.31 ± 0.75 | 2.1–2.5 | 2.13 ± 0.25 | 2–2.5 | 2.55 ± 0.52 | 2.3–2.7 | 2.4 ± 0.24 | 2.1–2.7 | 2.1–2.7 |
| Sodium | mEq/L | 136.58 ± 6.57 | 128–148 | 136.25 ± 5.25 | 133–144 | 143 ± 5.35 | 137–150 | 144.5 ± 9.98 | 130–152 | 121–159.5 |
| Potassium | mEq/L | 5.18 ± 0.54 | 4.5–6.2 | 5.15 ± 0.51 | 4.5–5.6 | 4.95 ± 0.3 | 4.8–5.4 | 4.58 ± 0.38 | 4.2–5.1 | 4–23.11 |
| Na:K | — | 26.67 ± 1.87 | 24–30 | 26.75 ± 2.5 | 24–30 | 29 ± 2.71 | 25–31 | 31.75 ± 4.79 | 25–36 | — |
| Chloride | mEq/L | 101.58 ± 4.89 | 94–112 | 98.25 ± 3.3 | 94–102 | 110 ± 2.83 | 106–112 | 111.5 ± 9.26 | 98–119 | 96–130.7 |
| Cholesterol | mg/dL | 59.17 ± 19.57 | 34–90 | 59.5 ± 23.81 | 34–84 | 69.75 ± 36.94 | 42–123 | 78 ± 20.05 | 57–105 | 20–133 |
| Triglycerides | mg/dL | 125.92 ± 53.35 | 45–213 | 105.5 ± 54.06 | 45–168 | 128.25 ± 40.28 | 75–165 | 156.75 ± 59.31 | 96–225 | 28–284 |
Different lowercase letters indicate significantly (P < 0.05) different values.