Table 2. Age- and Sex-Stratified Ocular Biometry and Lens NOP in CHES.
| Variable | Age Group | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Women | Men | |||||||||
| 50-59 y (n = 1407) |
60-69 y (n = 884) |
70-79 y (n = 223) |
≥80 y (n = 61) |
P Valuea | 50-59 y (n = 676) |
60-69 y (n = 551) |
70-79 y (n = 194) |
≥80 y (n = 75) |
P Valuea | |
| Age, mean (SD), y | 54.4 (3.3) | 63.0 (2.6) | 73.7 (2.9) | 83.5 (3.5) | NA | 54.8 (2.9) | 63.4 (2.8) | 73.6 (3.0) | 83.7 (3.9) | NA |
| SE, mean (SD) [range], D | −0.62 (2.95) [−19.63 to 5.13] | −0.53 (3.18) [−23.50 to 10.88] | 0.02 (2.41) [−12.25 to 4.63] | 0.60 (1.62) [−4.38 to 4.13] | <.001 | −0.69 (3.00) [−22.50 to 7.50] | −0.77 (3.01) [−20.63 to 4.25] | 0.15 (2.18) [−11.75 to 5.38] | 0.40 (2.29) [−8.38 to 4.88] | <.001 |
| CP, mean (SD) [range], D | 43.45 (1.55) [33.49 to 48.43] | 43.52 (1.50) [36.27 to 48.83] | 43.64 (1.28) [40.51 to 47.16] | 43.76 (1.58) [40.26 to 47.50] | .03 | 42.88 (1.47) [36.82 to 47.34] | 42.83 (1.45) [35.82 to 47.85] | 43.03 (1.35) [39.59 to 46.72] | 42.89 (1.50) [39.28 to 46.44] | .56 |
| AL, mean (SD) [range], mm | 23.62 (1.34) [20.76 to 33.30] | 23.69 (1.40) [20.84 to 34.73] | 23.44 (1.13) [20.88 to 29.35] | 23.17 (0.9) [21.05 to 25.44] | .08 | 24.14 (1.27) [20.80 to 30.68] | 24.29 (1.34) [21.31 to 33.33] | 23.91 (1.08) [21.39 to 29.07] | 23.93 (1.12) [22.37 to 28.22] | .26 |
| VCD, mean (SD) [range], mm | 15.28 (1.27) [11.29 to 24.56] | 15.33 (1.35) [12.17 to 26.01] | 15.08 (1.11) [13.11 to 20.73] | 14.81 (0.95) [12.4 to 17.13] | .03 | 15.66 (1.21) [12.60 to 22.35] | 15.72 (1.25) [13.05 to 24.34] | 15.38 (1.05) [13.10 to 20.76] | 15.41 (1.01) [13.94 to 19.28] | .02 |
| ACD, mean (SD) [range], mm | 3.39 (0.32) [1.98 to 4.84] | 3.29 (0.34) [2.09 to 4.62] | 3.15 (0.33) [2.27 to 4.10] | 3.05 (0.44) [2.01 to 4.26] | <.001 | 3.50 (0.33) [2.26 to 4.54] | 3.43 (0.33) [2.32 to 4.60] | 3.29 (0.35) [2.38 to 4.49] | 3.25 (0.37) [2.41 to 4.08] | <.001 |
| CCT, mean (SD) [range], µm | 558 (35) [407 to 673] | 557 (33) [439 to 707] | 555 (33) [462 to 646] | 552 (28) [492 to 594] | .16 | 565 (36) [428 to 677] | 563 (33) [473 to 673] | 562 (35) [475 to 671] | 559 (38) [491 to 644] | .07 |
| LT, mean (SD) [range], mm | 4.39 (0.34) [3.16 to 7.85] | 4.53 (0.36) [2.94 to 6.85] | 4.66 (0.40) [2.84 to 6.21] | 4.76 (0.54) [3.55 to 6.40] | <.001 | 4.37 (0.34) [2.77 to 7.12] | 4.57 (0.36) [3.06 to 6.48] | 4.68 (0.41) [2.89 to 5.80] | 4.71 (0.56) [2.32 to 6.00] | <.001 |
| Lens NOP grade, No. (%)b | ||||||||||
| N0 | 44 (3.1) | 3 (0.3) | 0 | 0 | <.001 | 20 (3.0) | 3 (0.5) | 0 | 0 | <.001 |
| NI | 1119 (79.5) | 504 (57.1) | 71 (31.8) | 13 (21.7) | 544 (80.6) | 336 (61.0) | 69 (35.6) | 14 (18.7) | ||
| NII | 236 (16.8) | 343 (38.8) | 113 (50.7) | 24 (40.0) | 108 (16.0) | 192 (34.8) | 104 (53.6) | 42 (56.0) | ||
| NIII | 6 (0.4) | 27 (3.1) | 36 (16.1) | 18 (30.0) | 1 (0.1) | 15 (2.7) | 21 (10.8) | 15 (20.0) | ||
| NIV | 2 (0.1) | 6 (0.7) | 3 (1.3) | 5 (8.3) | 2 (0.3) | 5 (0.9) | 0 | 4 (5.3) | ||
Abbreviations: ACD, anterior chamber depth; AL, axial length; CCT, central corneal thickness; CHES, Chinese American Eye Study; CP, corneal power; D, diopter; LT, lens thickness; NA, not applicable; NOP, nuclear opalescence; SE, spherical equivalent; VCD, vitreous chamber depth.
a
Calculated using the test for trend by age groups.
b
Graded using the Lens Opacities Classification System II, with higher grades indicating increasing severity. Percentages have been rounded and may not total 100.