Table 4. Overall and Age-Stratified Multiple Linear Regression Models Demonstrating Ocular Determinants of RE in CHESa.
| Variable | All Participants | P Value | ||
|---|---|---|---|---|
| Regression (95% CI) | SRC | SPCC | ||
| Model 1a | ||||
| AL | −2.01 (−2.05 to −1.97) | −0.92 | 0.55 | <.001 |
| CP | −0.82 (−0.86 to −0.78) | −0.43 | 0.15 | <.001 |
| NOP | −0.15 (−0.24 to −0.06) | −0.03 | 0.0008 | .002 |
| Model R2 value | 0.71 | NA | NA | NA |
| Model 2a | ||||
| VCD | −2.28 (−2.32 to −2.23) | −0.99 | 0.52 | <.001 |
| CP | −0.90 (−0.93 to −0.86) | −0.47 | 0.15 | <.001 |
| LT | −2.24 (−2.38 to −2.09) | −0.29 | 0.06 | <.001 |
| ACD | −0.50 (−0.66 to −0.34) | −0.059 | 0.002 | <.001 |
| CCT | −0.003 (−0.004 to −0.002) | −0.035 | 0.001 | <.001 |
| NOP | −0.07 (−0.15 to 0.02) | −0.01 | 0.0002 | .13 |
| Model R2 value | 0.74 | NA | NA | NA |
Abbreviations: ACD, anterior chamber depth; AL, axial length; CCT, central corneal thickness; CHES, Chinese American Eye Study; CP, corneal power; LT, lens thickness; NA, not applicable; NOP, nuclear opalescence; RE, refractive error; SRC, standardized regression coefficient; SPCC, semipartial correlation coefficient squared; VCD, vitreous chamber depth.
a
Model 1 uses AL and model 2 uses component parts of AL (VCD, LT, ACD, and CCT). Both were adjusted for age and sex. eTable 2 in the Supplement provides age-stratified results.