Table 2. Number of Benzodiazepine Fills Among Simultaneous New Users of an Antidepressant and a Benzodiazepine by Grace Period Used to Define Benzodiazepine Treatment Discontinuationa.
| Benzodiazepine Fills Before Treatment Discontinuation | No. (%) of Patients (n = 61 482)b | ||
|---|---|---|---|
| Primary Analysis: 30-d Grace Period | Sensitivity Analyses | ||
| 10-d Grace Period | 60-d Grace Period | ||
| 1 (no refill) | 39 369 (64.0) | 46 477 (75.6) | 35 189 (57.2) |
| 2 | 9237 (15.0) | 7057 (11.5) | 9696 (15.8) |
| 3 | 3796 (6.2) | 2656 (4.3) | 4300 (7.0) |
| ≥4 | 9080 (14.8) | 5292 (8.6) | 12 297 (20.0) |
a
Grace period indicates the number of days without medication between fills that is allowed before a patient was known to have discontinued benzodiazepine therapy.
b
Restricted to simultaneous new users with 6 months of follow-up (n = 61 482).