Table 2. Cox regression Models Comparing Hazard of Mortality by Percent of Cases With Lymph Node Yields of 18 or Morea.
Lymph Node ≥18 Threshold, % | Hospitals, No. | Patients, No. | HR (95% CI) | P Value |
---|---|---|---|---|
70 | 395 | 38 830 | 0.98 (0.95-1.01) | .23 |
75 | 290 | 31 819 | 0.97 (0.94-1.00) | .03 |
80 | 199 | 23 336 | 0.951 (0.92-0.98) | .001 |
85 | 118 | 12 877 | 0.927 (0.89-0.96) | <.001 |
90 | 47 | 3101 | 0.91 (0.85-0.97) | .005 |
Abbreviation: HR, hazard ratio.
Model includes sex, age, race, comorbidities, site, cN stage, pT stage, number of positive nodes, receipt of adjuvant therapy, extracapsular extension, insurance, income, education level, hospital volume, and hospital type. Head and neck cancers; data from the National Cancer Database, 2004 to 2013.