Table 2. Univariable and Multivariable Analyses of the Association Between at Least Moderate PVR and 1-Year Outcomes.
| End Point | Univariable Analysis |
Multivariable Analysisa |
||
|---|---|---|---|---|
| HR (95% CI)b | P Value | HR (95% CI) | P Value | |
| All-cause mortality | 2.40 (1.30-4.43) | .005 | 2.59 (1.39-4.85) | .003 |
| Cardiovascular mortality | 2.68 (1.24-5.81) | .01 | 2.87 (1.30-6.30) | .009 |
| Rehospitalization | 2.27 (1.34-3.83) | .002 | 2.27 (1.31-3.94) | .003 |
| Composite of mortality and rehospitalization | 2.35 (1.52-3.62) | .001 | 2.36 (1.50-3.69) | <.001 |
| Aortic valve reintervention | 13.14 (3.39-50.85) | <.001 | NA | NA |
Abbreviations: HR, hazard ratio; NA, not applicable; PVR, paravalvular regurgitation; STS, Society of Thoracic Surgeons.
a
Adjusted for age, sex, body mass index, STS score, diabetes, at least moderate baseline aortic regurgitation, and at least moderate baseline mitral regurgitation.
b
Hazard ratio is for at least moderate PVR vs less than moderate PVR. Multivariable analysis was not performed for aortic valve reintervention because there were only 10 events.