. 2017 Nov 15;2(11):1208–1216. doi: 10.1001/jamacardio.2017.3425

Table 2. Univariable and Multivariable Analyses of the Association Between at Least Moderate PVR and 1-Year Outcomes.

End Point	Univariable Analysis		Multivariable Analysis^a
End Point	HR (95% CI)^b	P Value	HR (95% CI)	P Value
All-cause mortality	2.40 (1.30-4.43)	.005	2.59 (1.39-4.85)	.003
Cardiovascular mortality	2.68 (1.24-5.81)	.01	2.87 (1.30-6.30)	.009
Rehospitalization	2.27 (1.34-3.83)	.002	2.27 (1.31-3.94)	.003
Composite of mortality and rehospitalization	2.35 (1.52-3.62)	.001	2.36 (1.50-3.69)	<.001
Aortic valve reintervention	13.14 (3.39-50.85)	<.001	NA	NA

Abbreviations: HR, hazard ratio; NA, not applicable; PVR, paravalvular regurgitation; STS, Society of Thoracic Surgeons.

^{^a}

Adjusted for age, sex, body mass index, STS score, diabetes, at least moderate baseline aortic regurgitation, and at least moderate baseline mitral regurgitation.

^{^b}

Hazard ratio is for at least moderate PVR vs less than moderate PVR. Multivariable analysis was not performed for aortic valve reintervention because there were only 10 events.