Table 1. Transcatheter Aortic Valve Replacement (TAVR) and Surgical Aortic Valve Replacement (SAVR) Population Descriptions.
| Characteristic | TAVR Cohort, No./Total No.a (%) | SAVR Cohort, No./Total No.a (%) |
|---|---|---|
| PARTNER 1 cohort | ||
| Cohort A | 321/2482 (12.9) | 313/313 (100) |
| Cohort B | 165/2482 (6.6) | NA |
| Randomized continuing access cohort B | 39/2482 (1.6) | NA |
| Nonrandomized continuing access cohort A | 1742/2482 (70.2) | NA |
| Nonrandomized continuing access cohort B | 215/2482 (8.7) | NA |
| Baseline characteristics | ||
| Age, mean (SD), y | 84.5 (7.15) | 84.5 (6.33) |
| Female | 1179/2480 (47.5) | 134/313 (42.8) |
| White | 2342/2479 (94.5) | 294/313 (93.9) |
| Hypertension | 2280/2479 (92.0) | 294/313 (93.9) |
| Diabetes | 917/2482 (36.9) | 128/313 (40.9) |
| History of renal disease | 448/2482 (18.0) | 69/313 (22.0) |
| History of pulmonary disease | 1550/2478 (62.6) | 211/313 (67.4) |
| History of coronary artery disease | 1928/2479 (77.8) | 241/313 (77.0) |
| Presence of ≥1 preprocedure coronary artery stenosis >50% | 2216/2414 (91.8) | 264/288 (91.7) |
| History of myocardial infarction | 638/2467 (25.9) | 90/310 (29.0) |
| NYHA class 3 or 4 heart failure symptoms | 2354/2479 (95.0) | 297/313 (94.9) |
| Peripheral arterial disease | 1737/2482 (70.0) | 210/313 (67.1) |
| STS risk score >10 | 1552/2473 (62.8) | 231/313 (73.8) |
| Baseline echocardiogram data | ||
| LV mass, mean (SD), g | 250 (76.3) | 278 (86.2) |
| Visual ejection fraction, mean (SD), % | 52.5 (12.9) | 53.4 (12.4) |
| Doppler stroke volume index, mean (SD), mL/m2 | 34.9 (10.9) | 34.0 (10.7) |
| Peak AV gradient, mean (SD), mm Hg | 71.3 (22.4) | 73.3 (24.1) |
| Mean AV gradient, mean (SD), mm Hg | 44.0 (14.3) | 43.4 (14.3) |
| AV area, mean (SD), cm2 | 0.65 (0.19) | 0.64 (0.19) |
| Doppler velocity index, mean (SD), m/s | 0.20 (0.06) | 0.20 (0.05) |
| Aortic regurgitation (moderate or severe) | 261/2424 (10.8) | 43/302 (14.2) |
| Mitral regurgitation (moderate or severe) | 534/2419 (22.1) | 59/299 (19.7) |
| Procedural and postprocedural data | ||
| Access site for implantation: transapical | 1056/2482 (42.5) | NA |
| Prosthesis size, mm | ||
| 19 | NA | 37/310 (11.9) |
| 21 | NA | 124/310 (40.0) |
| 23 | 1277/2449 (52.1) | 109/310 (35.2) |
| 25 | NA | 37/310 (11.9) |
| 26 | 1172/2449 (47.9) | NA |
| 27 | NA | 3/310 (1.0) |
| Intraprocedural valve-in-valve | 56 (2.3) | NA |
| Prosthesis-patient mismatch, Y/N | ||
| Moderate | 717/2376 (30.2) | 88/285 (30.9) |
| Severe | 448/2376 (18.9) | 94/285 (33.0) |
Abbreviations: AV, aortic valve; LV, left ventricular; NA, not applicable; NYHA, New York Heart Association.
a
Patients with data available.