Table. Baseline Patient Characteristics of the Overall Study Cohort Before and After PS Weighting.
| Characteristic | MAG,a No. (%) (n = 5580) |
LITA+SVG (n = 14 496) |
Standardized Difference | ||
|---|---|---|---|---|---|
| Before PS Weighting,a No. (%) | After PS Weighting,b % | Before PS Weightingc | After PS Weightingc | ||
| Age at surgery, mean (SD), y | 60.0 (8.7) | 68.0 (8.9) | 60.3 (8.5) | 0.916 | 0.039 |
| Female sex | 586 (10.5) | 2803 (19.3) | 10.6 | 0.288 | 0.004 |
| Ejection fraction, <35% | 278 (5.0) | 1383 (9.5) | 5.1 | 0.210 | 0.006 |
| Ejection fraction, 35%-50% | 1914 (34.3) | 5416 (37.4) | 33.4 | 0.064 | 0.018 |
| Ejection-fraction, >50% | 3388 (60.7) | 7697 (53.1) | 61.5 | 0.156 | 0.015 |
| BMI | |||||
| <18.5 | 10 (0.2) | 99 (0.7) | 0.2 | 0.119 | 0 |
| 18.5-29 | 3785 (67.8) | 10001 (69.0) | 67.9 | 0.025 | 0.001 |
| 30-34 | 1349 (24.2) | 3188 (22.0) | 24.2 | 0.051 | 0.001 |
| >35 | 436 (7.8) | 1208 (8.3) | 7.7 | 0.019 | 0.003 |
| Urgent statusd | 1549 (27.8) | 3385 (23.4) | 27.8 | 0.098 | 0.002 |
| CCS class IV | 2529 (45.3) | 6194 (42.7) | 44.9 | 0.052 | 0.008 |
| NYHA IV | 99 (1.8) | 304 (2.1) | 1.5 | 0.024 | 0.019 |
| Left main disease | 1785 (32.0) | 4331 (29.9) | 32.2 | 0.045 | 0.004 |
| Previous PCI | 948 (17.0) | 2629 (18.1) | 17.0 | 0.031 | 0.001 |
| Prior myocardial infarction | 3085 (55.3) | 8945 (61.7) | 55.2 | 0.129 | 0.002 |
| Preoperative arrhythmia | 227 (4.1) | 1077 (7.4) | 4.2 | 0.170 | 0.005 |
| History of heart failure | 453 (8.1) | 2339 (16.1) | 8.0 | 0.294 | 0.003 |
| Hypertension | 4224 (75.7) | 12060 (83.2) | 76.0 | 0.175 | 0.006 |
| Pulmonary hypertension | 100 (1.8) | 630 (4.3) | 1.9 | 0.192 | 0.006 |
| PVD | 559 (10.0) | 2559 (17.7) | 10.0 | 0.254 | 0.001 |
| COPD | 816 (14.6) | 3028 (20.9) | 14.7 | 0.177 | 0.003 |
| Cerebrovascular diseasee | 318 (5.7) | 1919 (13.2) | 5.7 | 0.325 | 0.002 |
| Renal disease, normalf | 4600 (82.4) | 10056 (69.4) | 82.4 | 0.343 | 0 |
| Renal disease, dysfunctionf | 854 (15.3) | 3510 (24.2) | 15.3 | 0.247 | 0.001 |
| Renal disease, failure without dialysisf | 90 (1.6) | 696 (4.8) | 1.6 | 0.253 | 0.001 |
| Renal disease, dialysisf | 36 (0.6) | 234 (1.6) | 0.7 | 0.121 | 0.001 |
| Diabetes | 1650 (29.6) | 5771 (39.8) | 29.5 | 0.224 | 0.002 |
| Cancer within 5 y | 148 (2.7) | 701 (4.8) | 2.7 | 0.136 | 0.002 |
| Liver disease | 378 (6.8) | 1272 (8.8) | 6.8 | 0.080 | 0.003 |
| Moderate/severe anemiag | 156 (2.8) | 1048 (7.2) | 2.9 | 0.269 | 0.004 |
| Current/recent smoking within 1 mo | 988 (17.7) | 2013 (13.9) | 17.4 | 0.100 | 0.007 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CCS class, Canadian Cardiovascular Society Functional Classification of Angina; COPD, chronic obstructive pulmonary disease; LITA+SVG, left internal thoracic artery supplemented by saphenous vein grafts; MAG, multiple arterial grafting; NYHA class, New York Heart Association Class; PCI, percutaneous coronary intervention; PS, propensity score; PVD, peripheral vascular disease.
SI conversion factor: To convert hemoglobin to grams per liter, multiply by 10).
Data are expressed as number (%) of patients unless otherwise indicated.
Data are expressed as weighted percentage unless otherwise indicated.
The standardized differences of <0 .1 indicate adequate balance of the distribution of baseline risk between the 2 groups.
Urgent status indicates any instances when the patient had left main stenosis greater than 70%, unstable angina receiving nitroglycerin/heparin drip.
Cerebrovascular disease is defined as cerebrovascular accident or transient ischemic attack.
Renal disease is any documented history of renal disease diagnosed including dialysis, acute or chronic renal failure, or estimated glomerular filtration rate less than 60 mL/min/1.73m2 (by the Cockcroft-Gault formula). Dialysis: patient is currently undergoing either hemodialysis or peritoneal dialysis. Failure without dialysis: acute or chronic renal failure or estimated glomerular filtration rate less than 15 mL/min/1.73m2 without dialysis. Dysfunction estimated glomerular filtration rate between 15 and 60 mL/min/1.73m2.
Moderate/severe anemia is defined as hemoglobin level less than 11 g/dL.