Table 5. Genotype and Allele Frequencies of the Vitamin D Receptor Polymorphisms.
| Genotype and Allele Frequency | No. (%) | P Value | Odds Ratio (95% CI) | ||
|---|---|---|---|---|---|
| Cases | Controls | Crude | Adjusteda | ||
| ApaI | |||||
| AA | 21 (22) | 24 (24) | .03b | 1.0 [Reference] | 1.0 [Reference] |
| Aa | 35 (37) | 52 (52) | 0.77 (0.37-1.59) | 0.79 (0.37-1.73) | |
| aa | 39 (41) | 24 (24) | 1.86 (0.86-4.03) | 1.52 (0.66-3.50) | |
| AA + Aa | 56 (59) | 76 (76) | .01c | 0.45 (0.25-0.84) | 0.57 (0.29-1.10) |
| A allele frequency | 0.405 | 0.500 | |||
| BsmI | |||||
| BB | 28 (29) | 43 (43) | .10b | 1.0 [Reference] | 1.0 [Reference] |
| Bb | 48 (50) | 42 (42) | 1.75 (0.93-3.30) | 1.78 (0.90-3.51) | |
| bb | 21 (22) | 15 (15) | 2.15 (0.95-4.86) | 1.35 (0.56-3.23) | |
| Bb + bb | 69 (71) | 57 (57) | .04c | 1.86 (1.03-3.36) | 1.65 (0.87-3.11) |
| b allele frequency | 0.464 | 0.360 | |||
| TaqI | |||||
| TT | 32 (33) | 45 (45) | .20b | 1.0 [Reference] | 1.0 [Reference] |
| Tt | 46 (47) | 41 (41) | 1.56 (0.85-2.93) | 1.61 (0.82-3.14) | |
| tt | 19 (20) | 14 (14 | 1.91 (0.84-4.36) | 1.25 (0.51-3.06) | |
| Tt + tt | 65 (67) | 55 (55) | .08c | 1.66 (0.93-2.96) | 1.50 (0.81-2.81) |
| t Allele frequency | 0.382 | 0.345 | |||
a
Adjusted for age and sex in a logistic model.
b
Distribution of 3 genotypes.
c
Distribution of combined genotypes.