Table 1. Model Variables for Measles Epidemiology, Vaccination, and Public Sector Costs.
Variable | Base Case Value | Comments |
---|---|---|
Fixed model parameters | ||
Estimated annual cases in US children in recent years | 48 | 28% Total cases were in ages 2-11 y |
Estimated annual No. of outbreaks in US children (≥3 cases) | 4 | |
MMR efficacy for measles, % | 95 | Assume some with 2 doses |
Cost per measles case, $ | 20 000 | |
Fitted model parameters | ||
Basic R0, measles in children | 5.7a | |
No. of measles importations in US children | 16b |
Abbreviations: CDC, Centers for Disease Control and Prevention; MMR, measles, mumps, and rubella; R0, reproductive number.
The model accounts for transmission among children who represent approximately 30% of the cases.
The CDC estimates approximately 35 cases of imported measles per year, which broadly aligns with our findings because children account for approximately 30% of the cases.