Skip to main content
. 2017 Sep 13;153(9):882–891. doi: 10.1001/jamadermatol.2017.0504

Table 1. Clinical Characteristics of Patients.

Characteristic No. (%) Melanotic Macules vs Melanomas, P Value
Group 1 Group 2
Normal Lips
(n = 10)
Melanotic Macules
(n = 16)
Melanomasa
(n = 6)
Age, mean (SD), y 34.5 (6.1) 49.6 (17.9) 56.2 (15.5) .46
Sex
Male 3 (30) 3 (19) 2 (40) .55
Female 7 (70) 13 (81) 3 (60)
Localization
Upper lip 0 1 (6) 5 (83) .001
Lower lip 10 (100) 15 (94) 1 (17)
Anatomic areab .009
Skin/vermillion 0 (0) 2 (33)
Vermillion 7 (44) 2 (33)
Vermillion/inner mucosae 8 (50) 0
Inner mucosae 1 (6) 2 (33)
Personal history of melanoma .61
Yes 0 4 (25) 3 (50)
No 10 (100) 10 (63) 3 (50)
NA 0 2 (12) 0
Family history of melanoma >.99
Yes 0 1 (6) 0
No 10 (100) 12 (75) 5 (83)
NA 3 (19) 1 (17)
Phototype .31
1 0 2 (12) 1 (17)
2 3 (30) 2 (12) 3 (50)
3 5 (50) 7 (44) 1 (17)
4 2 (20) 1 (6) 0
NA 0 4 (25) 1 (17)

Abbreviation: NA, not available.

a

Two cases were primary melanomas (2 patients) and 4 cases were recurrent melanomas (3 patients).

b

In normal lips, the vermillion border, vermillion, and inner mucosae were examined.