Table 3. Annual Medication Adherence, Proportion of Days Covered (PDC).
| Medication | Control | Intervention | Difference (95% CI) | P Value | ||
|---|---|---|---|---|---|---|
| No. | PDC, Mean (SD) | No. | PDC, Mean (SD) | |||
| Strict definition | ||||||
| Statin | 337 | 0.69 (0.36) | 682 | 0.72 (0.35) | 0.03 (−0.02 to 0.07) | .23 |
| β-Blocker | 337 | 0.67 (0.37) | 682 | 0.69 (0.36) | 0.02 (−0.03 to 0.07) | .38 |
| Antiplatelet agent | 337 | 0.61 (0.41) | 682 | 0.64 (0.40) | 0.03 (−0.20 to 0.08) | .25 |
| All 3 medicationsa | 337 | 0.42 (0.39) | 682 | 0.46 (0.39) | 0.04 (−0.01 to 0.09) | .10 |
| Intermediate definition | ||||||
| Statin | 298 | 0.78 (0.27) | 611 | 0.80 (0.26) | 0.02 (−0.02 to 0.06) | .26 |
| β-Blocker | 297 | 0.76 (0.30) | 606 | 0.77 (0.29) | 0.02 (−0.02 to 0.06) | .38 |
| Antiplatelet agent | 267 | 0.77 (0.30) | 558 | 0.79 (0.29) | 0.01 (−0.03 to 0.06) | .54 |
| All 3 medicationsa | 246 | 0.58 (0.35) | 516 | 0.61 (0.33) | 0.04 (−0.01 to 0.09) | .16 |
| Relaxed definition | ||||||
| Statin | 298 | 0.81 (0.26) | 611 | 0.83 (0.25) | 0.02 (−0.02 to 0.06) | .27 |
| β-Blocker | 297 | 0.80 (0.28) | 606 | 0.81 (0.27) | 0.02 (−0.02 to 0.05) | .43 |
| Antiplatelet agent | 267 | 0.80 (0.29) | 558 | 0.81 (0.28) | 0.01 (−0.03 to 0.05) | .50 |
| All 3 medicationsa | 246 | 0.63 (0.34) | 516 | 0.66 (0.33) | 0.03 (−0.02 to 0.08) | .19 |
a
Calculated by the proportion of days in which a patient has an active medication for all 3 medications. It is not the weighted average of individual medication adherence.