Table 2. Relative Risk of and Tetrachoric Correlation for AF in First-Degree Relatives.
Sex of Affected Relative | Sex of Individual | No. of Cases | Prevalence, %a | Relative Risk (95% CI)b | Tetrachoric Correlation (95% CI)b |
---|---|---|---|---|---|
Any Relative | |||||
Male | Male | 1248 | 1.2 | 2.20 (2.06-2.35) | 0.10 (0.09-0.10) |
Female | 701 | 0.9 | 2.01 (1.87-2.16) | 0.11 (0.10-0.11) | |
All | 1949 | 1.1 | 2.20 (2.09-2.31) | 0.10 (0.10-0.11) | |
Female | Male | 1352 | 1.7 | 1.79 (1.70-1.88) | 0.18 (0.18-0.19) |
Female | 335 | 0.7 | 1.59 (1.40-1.81) | 0.11 (0.10-0.11) | |
All | 1687 | 1.4 | 1.79 (1.71-1.88) | 0.17 (0.16-0.17) | |
All | Male | 2493 | 1.4 | 1.93 (1.85-2.01) | 0.11 (0.11-0.12) |
Female | 1016 | 0.8 | 1.84 (1.73-1.96) | 0.08 (0.07-0.08) | |
All | 3509 | 1.2 | 1.96 (1.88-2.04) | 0.10 (0.10-0.11) | |
Parent | |||||
Male | Male | 784 | 0.8 | 2.03 (1.89-2.17) | 0.30 (0.29-0.31) |
Female | 139 | 0.2 | 1.43 (1.21-1.69) | 0.22 (0.20-0.23) | |
All | 923 | 0.6 | 1.98 (1.86-2.11) | 0.29 (0.28-0.29) | |
Female | Male | 1264 | 1.7 | 1.78 (1.69-1.88) | 0.36 (0.35-0.37) |
Female | 224 | 0.5 | 1.46 (1.28-1.66) | 0.31 (0.30-0.33) | |
All | 1488 | 1.3 | 1.77 (1.69-1.86) | 0.36 (0.35-0.36) | |
All | Male | 1973 | 1.2 | 1.83 (1.76-1.91) | 0.32 (0.32-0.33) |
Female | 349 | 0.3 | 1.42 (1.28-1.58) | 0.26 (0.25-0.27) | |
All | 2322 | 0.8 | 1.81 (1.74-1.89) | 0.32 (0.31-0.32) | |
Offspring | |||||
Male | Male | 362 | 12.2 | 2.72 (2.47-2.99) | 0.33 (0.32-0.34) |
Female | 535 | 9.8 | 2.28 (2.11-2.47) | 0.36 (0.35-0.37) | |
All | 897 | 10.7 | 2.50 (2.35-2.65) | 0.34 (0.33-0.35) | |
Female | Male | 65 | 6.5 | 1.84 (1.47-2.32) | 0.20 (0.18-0.23) |
Female | 105 | 6.6 | 1.92 (1.60-2.30) | 0.29 (0.27-0.31) | |
All | 170 | 6.6 | 1.93 (1.67-2.23) | 0.25 (0.23-0.26) | |
All | Male | 426 | 10.8 | 2.53 (2.32-2.77) | 0.31 (0.30-0.31) |
Female | 639 | 9.1 | 2.22 (2.06-2.38) | 0.35 (0.34-0.35) | |
All | 1065 | 9.7 | 2.39 (2.26-2.52) | 0.32 (0.32-0.33) | |
Full Sibling | |||||
Male | Male | 121 | 2.6 | 2.45 (1.97-3.04) | 0.36 (0.34-0.38) |
Female | 31 | 0.9 | 1.68 (1.19-2.38) | 0.32 (0.29-0.35) | |
All | 152 | 1.8 | 2.27 (1.88-2.74) | 0.35 (0.34-0.37) | |
Female | Male | 26 | 1.6 | 1.91 (1.31-2.79) | 0.33 (0.30-0.36) |
Female | 9 | 0.7 | 3.14 (1.37-7.19) | 0.25 (0.25-0.06) | |
All | 35 | 1.2 | 2.13 (1.49-3.03) | 0.31 (0.29-0.34) | |
All | Male | 147 | 2.3 | 2.34 (1.93-2.83) | 0.36 (0.34-0.37) |
Female | 40 | 0.8 | 1.88 (1.36-2.61) | 0.31 (0.29-0.34) | |
All | 187 | 1.7 | 2.25 (1.88-2.68) | 0.35 (0.33-0.36) | |
Twin | |||||
Male | Male | 4 | 16.7 | 17.37 (3.9-77.40) | 0.71 (0.63-0.80) |
Female | 0 | 0 | NA | NA | |
All | 4 | 13.3 | 14.78 (3.38-64.71) | 0.70 (0.62-0.79) | |
Female | Male | 0 | NA | NA | NA |
Female | 0 | NA | NA | NA | |
All | 0 | NA | NA | NA | |
All | Male | 4 | 14.3 | 14.14 (3.36-59.51) | 0.70 (0.61-0.78) |
Female | 0 | NA | NA | NA | |
All | 4 | 9.1 | 12.15 (2.94-50.21) | 0.65 (0.57-0.73) | |
Spouse | |||||
Female | Male | 1311 | 5.4 | 1.18 (1.12-1.24) | 0.25 (0.24-0.25) |
Male | Female | 1819 | 2.8 | 1.14 (1.09-1.19) | 0.23 (0.22-0.23) |
All | All | 3130 | 3.5 | 1.15 (1.10-1.20) | 0.22 (0.21-0.22) |
Abbreviations: AF, atrial fibrillation; NA, not applicable (because of no AF cases with affected twin).
Prevalence was equal to recurrence risk.
Adjusted for age, sex, occupation, income level, urbanization of residence, and family size.