Table 2. Number of Events and Crude and Weighted Event Rates According to Treatmenta.
Apixaban | Dabigatran | Rivaroxaban | Warfarin | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Events | Rate | Events | Rate | Events | Rate | Events | Rate | |||||
Crude | Weighted | Crude | Weighted | Crude | Weighted | Crude | Weighted | |||||
1-y Follow-up | ||||||||||||
Ischemic stroke/SE | 10 | 0.68 | 0.83 | 22 | 0.70 | 0.65 | 14 | 1.09 | 1.20 | 57 | 0.79 | 0.81 |
All-cause death | 19 | 1.62 | 1.52 | 51 | 1.62 | 1.84 | 26 | 2.01 | 1.67 | 249 | 3.45 | 3.11 |
Any bleeding | 8 | 0.68 | 0.57 | 23 | 0.74 | 0.73 | 17 | 1.33 | 1.38 | 109 | 1.52 | 1.53 |
Intracranial/gastrointestinal bleeding | <5 | 0.09 | 0.06 | 6 | 0.19 | 0.16 | <5 | 0.23 | 0.29 | 39 | 0.54 | 0.54 |
2.5-y Follow-up | ||||||||||||
Ischemic stroke/SE | 14 | 0.85 | 0.85 | 41 | 0.61 | 0.58 | 16 | 0.75 | 0.81 | 109 | 0.70 | 0.69 |
All-cause death | 22 | 1.32 | 1.21 | 91 | 1.33 | 1.48 | 49 | 2.28 | 2.10 | 428 | 2.71 | 2.47 |
Any bleeding | 11 | 0.67 | 0.56 | 44 | 0.65 | 0.65 | 22 | 1.04 | 1.09 | 202 | 1.30 | 1.31 |
Intracranial/gastrointestinal bleeding | <5 | 0.12 | 0.12 | 17 | 0.25 | 0.21 | 6 | 0.28 | 0.30 | 72 | 0.46 | 0.45 |
Abbreviations: IPTW, inverse probability of treatment weighed; SE, systemic embolism.
Crude rates are events divided by person time per 100 years; weighted rates are based on IPTW population and express population mean treatment rates per 100 years. Main analysis.