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. 2017 Oct 20;18(11):904–915. doi: 10.1080/15384047.2017.1385678

Table 1.

Correlation of HN1L expression with clinicopathological features in NSCLC patients.

    HN1L expression
 
Clinical features Cases Normal (n = 51) Upregulated (n = 58) P value
Gender       0.450
 Male 90 44 (48.9%) 46 (51.1%)  
 Female 19 7 (36.8%) 12 (63.2%)  
Age (years old)       0.833
 ≤65 77 37 (48.1%) 40 (51.9%)  
 >65 32 14 (43.7%) 18 (56.3%)  
Smoking       1.000
 Smokers 29 14 (48.3%) 15 (51.7%)  
 Never smokers 80 37 (46.2%) 43 (53.8%)  
Histological subtype       0.661
 SCC 79 31 (39.2%) 48 (60.8%)  
 ADC 30 10 (33.3%) 20 (66.7%)  
Differentiated degree       1.000
 I+II 77 36 (46.8%) 41 (53.2%)  
 III 32 15 (46.9%) 17 (53.1%)  
Adjacent organs invasion       0.830
 Negative 30 15 (50.0%) 15 (50.0%)  
 Positive 79 36 (45.6%) 43 (54.4%)  
Tumor size (cm)       0.022
 ≤4 47 28 (59.6%) 19 (40.4%)  
 >4 62 23 (37.1%) 39 (62.9%)  
Lymph node metastasis       0.567
 Negative 55 24 (43.6%) 31 (56.4%)  
 Positive 54 27 (50.0%) 27 (50.0%)  
Clinical stage       1.000
 I+II 70 33 (47.1%) 37 (52.9%)  
 III+IV 39 18 (46.2%) 21 (53.8%)

SCC, squamous carcinoma; ADC, adenocarcinoma. Statistical significance (P < 0.05) is shown in bold.