. Author manuscript; available in PMC: 2018 Nov 28.

Published in final edited form as: Langmuir. 2017 Nov 13;33(47):13669–13679. doi: 10.1021/acs.langmuir.7b01841

Table 2.

Vesicle collapse caused by daptomycin in POPC:POPG GUVs.

Lipid PC:PG	[Ca²⁺] (mM)	Observation time (min)	GUVs		% GUVs
Lipid PC:PG	[Ca²⁺] (mM)	Observation time (min)	Total	Collapsed	Collapsed
In the presence of 2 μM daptomycin
70:30	2	40	16	10	63
70:30	20	40	37	4	11
70:30	2	30	120	43	33
80:20	2	30	134	46	34
80:20	20	120	259	137	53
80:20	20	60	141	30	21
80:20	20	60	146	38	26
total (all trials)			863	308	36
In the absence of daptomycin
70:30	20	90	14	0	0
80:20	20	40	210	12	6
80:20	20	40	108	1	1
80:20	2	50	141	0	0
total (all trials)			473	13	3