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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Neurobiol Dis. 2017 Oct 16;109(Pt A):137–147. doi: 10.1016/j.nbd.2017.10.011

Figure 1.

Figure 1

Ictal discharges can be triggered by optogenetic stimulation of PV- or SOM-positive interneurons. A, Ictal discharge evoked by 0.2 Hz series of 1 s light pulses stimulating PV-positive interneurons during bath application of 4AP; ictal onset is expanded to show the timing of the light pulse in relation to ictal onset (box). B, The same stimulation parameters applied to SOM-positive interneurons also triggers ictal discharges.