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. 2017 Oct 11;8(53):90766–90780. doi: 10.18632/oncotarget.21798

Table 1. CPS induces UPS gene expression changes.

Ref Seq Symbol Description Fold change CPS-treated vs untreated
NM_007527 Bax Bcl2-associated X protein -2.04±0.03*
NM_013760 Dnajb9 Dnaj (Hsp40) homolog, subfamily B, member 9 -2.09±0.08*
NM_022310 Hspa5 Heat shock protein 5 -2.79±0.02*
NM_153526 Insig1 Insulin induced gene 1 -3.31±0.02*
NM_172307 Mbtps2 Membrane-bound transcription factor peptidase, site 2 -2.10±0.02*
NM_133933 Rpn1 Ribophorin 1 -2.40±0.04*
NM_013842 Xbp1 X-box binding protein 1 -2.67±0.05*
NM_013558 Hspa1l Heat shock protein 1-like -2.27±0.43*
NM_024207 Derl1 Der1-like domain family, member 1 +2.65±0.03*
NM_033562 Derl2 Der1-like domain family, member 2 +2.09±0.02*
NM_026184 Ero1lb ERO1-like beta (S.Cerevisiae) +2.10±0.04*

RT-PCR array in mRNA samples from thymocytes untreated and treated with CPS for 60 min. The expression levels were normalized using the housekeeping gene GAPDH and calculated by the ∆∆Ct method. Data, shown as fold change, represent the mean ± SD of three experiments. Untreated thymocyte mRNA was used as calibrator. *p < 0.01 vs untreated cells.