Table 1. Basic characteristics of subjects (n = 65).
| Characteristic | Patientsa | |||
|---|---|---|---|---|
| Untreated | Recurrent | Treated | Control | |
| Subjects number | 21 | 12 | 19 | 13 |
| Median age, years (range) | 60 (32–74) | 58.5 (53–77) | 61 (39–75) | 58 (49–75) |
| Gender | ||||
| Male | 8 | 6 | 14 | 10 |
| Female | 13 | 6 | 5 | 3 |
| Tumor stage | ||||
| III | 2 | 2 | 2 | / |
| IV | 19 | 10 | 17 | / |
| EGFRb status | ||||
| Mutation positive | / | |||
| Exon 19 | 6 | 3 | 4 | |
| Exon 21 | 2 | 6 | 5 | |
| Mutation negative | 4 | 0 | 6 | / |
| Unknown | 9 | 3 | 3 | / |
aUntreated patients did not receive any therapies, recurrent patients had stopped anti-cancer treatment for at least 6 months, and treated ones were under treatment. bEGFR, epidermal growth factor receptor