Table 1. The relative and absolute IC50 values of the chemotherapeutic agents tested in this study.
IC50 (μM) | [A]/[C] × 100 (%) | [B]/[C] × 100 (%) | |||
---|---|---|---|---|---|
HKBMM [A] | M-16-N [B] | IMR90 [C] | |||
Gemcitabine | 0.00365 | 0.0888 | 2.15 | 0.170 | 4.12 |
5-fluorouracil | 5.17 | 110 | 281 | 1.84 | 39.2 |
Methotrexate | 0.979 | 35.4 | 34.5 | 2.84 | 103 |
Irinotecan | 0.827 | 11.9 | 17.0 | 4.87 | 70.0 |
Temozolomide | 58.2 | 396 | 230 | 25.3 | 172 |
Paclitaxel | 0.00450 | 0.00421 | 0.0173 | 26.0 | 24.4 |
Cisplatin | 13.0 | 70.2 | 43.1 | 30.3 | 163 |
Carboplatin | 17.9 | 71.7 | 46.4 | 38.6 | 155 |
Sunitinib | 2.36 | 4.03 | 2.48 | 95.0 | 162 |
Hydroxyurea | 460 | 2580 | 279 | 165 | 924 |
Doxorubicin | 0.0179 | 0.0598 | 0.00928 | 193 | 644 |