Table 7. Adverse events during IC in the two arms.
| Adverse events | TPF arm | TP arm | Z | p | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | |||
| Hematologic | ||||||||||||
| Leukocytopenia | 1 | 4 | 19 | 29 | 4 | 8 | 22 | 31 | 10 | 4 | –4.874 | < 0.001 |
| Neutropenia | 1 | 6 | 8 | 20 | 22 | 14 | 15 | 29 | 12 | 5 | –5.758 | < 0.001 |
| Anemia | 39 | 14 | 3 | 1 | 0 | 51 | 15 | 7 | 2 | 0 | –0.233 | 0.816 |
| Thrombocytopenia | 45 | 2 | 9 | 1 | 0 | 60 | 5 | 10 | 0 | 0 | –0.278 | 0.781 |
| Liver function | 27 | 24 | 5 | 1 | 0 | 43 | 25 | 7 | 0 | 0 | –1.066 | 0.286 |
| Renal function | 56 | 1 | 0 | 0 | 0 | 75 | 0 | 0 | 0 | 0 | –1,147 | 0.251 |
| Non-hematologic | ||||||||||||
| Mucositis | 40 | 10 | 5 | 2 | 0 | 68 | 5 | 2 | 0 | 0 | –3.062 | 0.002 |
| Dermatitis | 52 | 5 | 0 | 0 | 0 | 69 | 6 | 0 | 0 | 0 | –0.158 | 0.874 |
| Diarrhea | 38 | 15 | 3 | 1 | 0 | 70 | 3 | 2 | 0 | 0 | –3.850 | < 0.001 |
| Nausea/vomiting | 45 | 7 | 4 | 1 | 0 | 67 | 5 | 2 | 1 | 0 | –1.644 | 0.100 |
Abbreviations: IC, induction chemotherapy.